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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
10.61
Human Site:
S135
Identified Species:
16.67
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S135
M
Y
L
Q
S
P
Q
S
E
R
T
D
P
H
G
Chimpanzee
Pan troglodytes
XP_510301
627
67581
P114
V
G
S
A
T
G
R
P
G
G
E
G
S
P
S
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
S135
M
Y
L
Q
S
P
Q
S
E
R
T
D
P
H
G
Dog
Lupus familis
XP_544614
968
105825
S422
M
Y
L
Q
S
P
Q
S
E
H
T
D
P
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
E136
Y
L
Q
S
P
Q
S
E
H
T
D
P
H
G
L
Rat
Rattus norvegicus
Q62829
544
60692
S31
D
S
S
A
L
N
H
S
S
K
P
L
P
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
P126
D
E
R
G
P
D
P
P
S
P
C
S
P
R
P
Chicken
Gallus gallus
XP_426393
667
74767
A135
Q
S
P
E
A
E
W
A
D
K
Y
G
N
Y
L
Frog
Xenopus laevis
NP_001082100
650
73749
E130
V
R
V
R
Q
Q
R
E
D
G
Q
R
G
S
E
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
L135
D
G
Y
Q
Y
E
T
L
D
D
P
E
P
H
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
E126
P
G
M
M
M
P
P
E
T
G
G
I
V
L
P
Honey Bee
Apis mellifera
XP_001122147
624
70155
S111
A
R
S
N
S
L
R
S
S
S
P
P
K
L
R
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
K59
M
K
K
N
K
D
K
K
E
A
S
E
K
P
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
K286
Y
Y
S
S
S
S
K
K
R
K
S
G
S
N
S
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
E284
A
E
Q
L
P
P
S
E
K
P
S
K
S
E
S
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
0
100
93.3
N.A.
0
13.3
N.A.
6.6
0
0
20
N.A.
6.6
13.3
13.3
N.A.
P-Site Similarity:
100
20
100
93.3
N.A.
0
20
N.A.
6.6
40
33.3
33.3
N.A.
13.3
20
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
14
7
0
0
7
0
7
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
20
0
0
0
0
14
0
0
20
7
7
20
0
0
0
% D
% Glu:
0
14
0
7
0
14
0
27
27
0
7
14
0
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
20
0
7
0
7
0
0
7
20
7
20
7
7
20
% G
% His:
0
0
0
0
0
0
7
0
7
7
0
0
7
27
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
0
7
7
0
7
0
14
14
7
20
0
7
14
0
0
% K
% Leu:
0
7
20
7
7
7
0
7
0
0
0
7
0
14
14
% L
% Met:
27
0
7
7
7
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
0
14
0
7
0
0
0
0
0
0
7
7
0
% N
% Pro:
7
0
7
0
20
34
14
14
0
14
20
14
40
14
14
% P
% Gln:
7
0
14
27
7
14
20
0
0
0
7
0
0
0
0
% Q
% Arg:
0
14
7
7
0
0
20
0
7
14
0
7
0
7
7
% R
% Ser:
0
14
27
14
34
7
14
34
20
7
20
7
20
7
20
% S
% Thr:
0
0
0
0
7
0
7
0
7
7
20
0
0
0
0
% T
% Val:
14
0
7
0
0
0
0
0
0
0
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% W
% Tyr:
14
27
7
0
7
0
0
0
0
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _